A recent experiment with cloning mice and the subsequent fertility problems that resulted are directly related to the fertility problems predicted by THE FROZEN GENE and which serve as the basis for the BIOSTELLAR novels. To be honest, it’s been a bit disappointing that people haven’t paid anywhere nearly as much attention to the core problem addressed by TFG as they have to the disproof of evolution by natural selection, especially now we know that the problem I identified in the human genome on the basis of the math and logic has a sound basis in empirical scientific data as well.
A twenty-year experiment at the University of Yamanashi just ended in the most predictable way imaginable—if you’ve been paying attention to the math. A team led by developmental biologist Teruhiko Wakayama took a single female mouse in 2005, cloned her, then cloned the clone, then cloned the clone of the clone, and kept going for two decades. Over 30,000 cloning attempts. More than 1,200 mice produced. Fifty-eight generations from that single original donor.
If you’ve read SIGMA GAME, then you probably already know what was coming: model collapse.
Generation 58 was the last. Every mouse born from it died within days......
Sexual reproduction is necessary for maintaining the genome. But it is not sufficient. Selection is the engine. Sex is the transmission. You can have the finest gearbox ever engineered, but if the engine is dead, the car isn’t going anywhere.
The engine is dying. The Yamanashi experiment just showed us, in a twenty-year time-lapse, what happens at the end of that road, in approximately 1,150 years from 1900 Anno Domini.
The problem of the frozen gene is real. We had better pay attention.
