Treating Depression as a Whole-Body Disease (Part3)

 The Five Axes of Depression

Depression can be understood across five key biological domains:

1. Inflammation

2. Metabolism

3. Neurotransmission & neuroplasticity

4. Circadian rhythm

5. Gut–brain axis & micronutrients

Each contributes to the illness.

Each must be addressed.

https://paulmarik.substack.com/p/treating-depression-as-a-whole-body?publication_id=5737269&utm_campaign=email-post-title&r=y7h5a&utm_medium=email